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  • Product Description
  • Safety Information
  • Side Effects

What is Levitra?

Generic Levitra - a drug for the treatment of erectile dysfunction, an inhibitor of phosphodiesterase type 5 (PDE5).
Erection is a hemodynamic process, based on the relaxation of smooth muscles of cavernous bodies and located in its arterioles.

During sexual stimulation of the nerve endings of cavernous bodies released nitric oxide (N0), activating the enzyme guanylate cyclase, which leads to higher content in the cavernous bodies of cyclic guanosine monophosphate (cGMP). The result is relaxation of smooth muscles of cavernous bodies, which increases blood flow to the penis.

Levitra (Vardenafil) blocks PDE5, which is under the influence of the splitting of cGMP, pursuant to the action of endogenous NO in the cavernous bodies during sexual stimulation, increases, resulting in the ability to Levitra enhances the natural response to sexual stimulation.

Dosing.

Dose of 5 mg is recommended for older patients (over 65). In the future, depending on the efficacy and tolerability of Levitra dose may be increased to 10 mg.
In patients with moderate hepatic impairment declines Vardenafil clearance, so the starting dose of Generic Levitra should be 5 mg day. In patients with minor hepatic impairment Levitra dosing regime change is not required.
Patients with minor, moderate and severely impaired renal function change the dosage Levitra is not required.
Do not take Levitra more than once a day.
The maximum recommended dose is 20 mg 1 time per day.

How to use?

Levitra can be taken irrespective of meals. Levitra is effective only when a sufficient level of sexual stimulation.
Levitra the recommended dose of 10 mg should be taken for 25-60 minutes before intercourse. Levitra duration of action is 4-5 hours.
In the absence of positive effect to increase the dose of Levitra 20 mg (diabetes, prostatectomy).
Patients taking other medications or conditions involving reduced metabolism of Vardenafil, the dose of Levitra should be 2,5-5 mg.

Overdose.

We know of cases receiving Levitra in the dose of 80 mg per day, which is not accompanied by the development of serious adverse reactions. However, at the same time when used in a dose of 40 mg. twice a day, there is a pronounced low back pain with no signs of toxic effects on muscle and nervous system.
Treatment: the holding of symptomatic and supportive therapy. Since Vardenafil is highly bound to plasma proteins and only a small number Generic Levitra excreted by the kidneys, the effectiveness of hemodialysis is unlikely.

Side effects.

Levitra generally well tolerated, side effects, usually slightly or moderately expressed and are transient in nature.

When conducting clinical trials of Levitra celebrated adverse reactions were: Headache, dizziness, blurred vision, drowsiness, increased muscle tone; Dyspepsia, nausea, change in functional "liver" tests, increased GGTP;

"Tides" of blood to the face, hypertension, sync opal states, myocardial ischemia, epistaxis; Rhinitis, dyspnea; Anaphylactic reaction (including laryngeal edema), photosensitivity; Increased creatine kinase, myalgia, back pain; Glaucoma; Priapism.

Cautions and precautions.

Since a sexual activity is associated with a certain degree of fundamental risk, before the appointment of Levitra erectile dysfunction on the need to evaluate the state of the cardiovascular system of the patient. Levitra (Vardenafil) is not intended for use in children.

Warnings/Precautions

Do not use Levitra if:

  • you are allergic to any ingredient in Levitra;
  • you are taking or using nitroglycerin (eg, tablet, patch, ointment), nitrates (eg, isosorbide), or certain antiarrhythmics (eg, amiodarone, quinidine);
  • you have had a heart attack, stroke, or life-threatening irregular heartbeat within the past 6 months;
  • you have certain eye problems (eg, retina diseases such as retinitis pigmentosa), uncontrolled chest pain, uncontrolled high blood pressure, low blood pressure, irregular heartbeat (eg, congenital QT prolongation), severe heart failure, severe liver problems, or end-stage kidney disease that requires dialysis.
Contact your doctor or health care provider right away, if any of these apply to you.
Possible Side Effects

Stop using vardenafil and call your doctor at once, if you have any of these serious side effects:

  • sudden vision loss;
  • ringing in your ears, or sudden hearing loss;
  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
  • irregular heartbeat;
  • swelling in your hands, ankles, or feet;
  • shortness of breath;
  • vision changes;
  • feeling light-headed, fainting; or
  • penis erection that is painful or lasts 4 hours or longer.
Less serious side effects may include:
  • warmth or redness in your face, neck, or chest;
  • stuffy nose;
  • headache;
  • upset stomach; or
  • back pain.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. More Information

Levitra is available with a prescription under the brand name Levitra. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new for you.

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